A Less Invasive Intervention for Heart Failure Patients

The Revivent™ Myocardial Anchoring System differs from conventional surgical reconstructive approaches.

The Revivent System addresses the safety concerns of physicians about subjecting patients to invasive surgical interventions on the left ventricle (LV). The LIVE™ procedure can be performed as a separate stand-alone procedure, concomitant with other procedure (e.g. CABG) or during other occasions when a sternotomy is already employed. Neither a myocardial incision nor cardiopulmonary bypass is required. Additionally, the Revivent System is deployed using a straightforward, epicardial approach that can be completed in about one hour.

The importance of Laplace's law in treating the underlying cause of heart failure.

The LIVE procedure is based upon a well-defined law of physics called the Laplace's law, which describes the relationship between the radius and pressure of the LV, and the resulting LV wall tension. Increased wall tension is the underlying cause of LV enlargement, worsening heart failure symptoms and ultimately patient death. Conversely, reducing wall tension prevents further LV enlargement and stops the progression of the disease.

The Revivent System is uniquely designed to reduce wall tension by directly reducing the LV radius, which in turn decreases wall tension and interrupts the ongoing destructive process of ischemic heart failure. Restoring the LV to its more optimal, conical geometry, enhances the performance of the remaining myocardium.

A cross section of the LV depicting an anteroseptal scar with acontractile myocardium, which leads to LV dilatation and an increase in LV wall tension.

After placement of the Revivent System, the scarred, acontractile myocardium is excluded from the LV, immediately reducing LV circumference, volume and wall tension.